The Government has outlined how it will work to reduce, replace and refine the use of animals in research - known as 'the 3Rs'. The UK's National Centre for the 3Rs has been leading the way in this area, and has already invested over £35 million to support this work. As a result, trials into cancer, epilepsy, multiple sclerosis, as well as toxicity testing, have all seen reductions in animal use. However, please know that I do not sign EDMs as they are costly and hardly ever get debated; I much prefer to raise the issue with ministers themselves.